Index

Piperidine-Ring-Synthesis-N-Nu-Carboxyl-H

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = H, A-Aromatic-Carbon, A-Aliphatic-Carbon, Vinyl-Group

Reactants

Products

Piperidine-Ring-Synthesis-N-Nu-Amino

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group-No-Oxygen, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R11 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group-No-Oxygen, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen

Reactants

Products

Piperidine-Ring-Synthesis-N-Nu-Alkoxide

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Reactants

Products

Prins-Reaction-1

References: 0

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene-Aromatic, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Thiane-Ring-Synthesis-S-Nu-Hydroxyl

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Reactants

Products

Tetrahydropyran-Ring-Synthesis-Nu-Hydroxyl

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Reactants

Products

Tetrahydropyran-Ring-Synthesis-Nu-Carboxyl-H

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = H, A-Aromatic-Carbon, A-Aliphatic-Carbon, Vinyl-Group

Reactants

Products

Thiane-Ring-Synthesis-S-Nu-Alkoxide

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Reactants

Products

Prins-Reaction-3

References: 0

Special Conditions : SIDE REACTION

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
R3 = L-A, A-Aromatic-Carbon
R4 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
R5 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene-Aromatic, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Thiane-Ring-Synthesis-S-Nu-Amino

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group-No-Oxygen, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R11 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group-No-Oxygen, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen

Reactants

Products

Piperidine-Ring-Synthesis-N-Nu-Hydroxyl

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Reactants

Products

Tetrahydropyran-Ring-Synthesis-Nu-Amino

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group-No-Oxygen, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R11 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group-No-Oxygen, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen

Reactants

Products

Thiane-Ring-Synthesis-S-Nu-Carboxyl-H

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = H, A-Aromatic-Carbon, A-Aliphatic-Carbon, Vinyl-Group

Reactants

Products

Prins-Reaction-2

References: 0

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene-Aromatic, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Tetrahydropyran-Ring-Synthesis-Nu-Alkoxide

References: 0,1

Condition to enforce:

R1 = L-A, A-Aromatic-Carbon
R2 = L-A, A-Aromatic-Carbon
R3 = L-A, A-Aromatic-Carbon
R4 = L-A, A-Aromatic-Carbon
R5 = L-A, A-Aromatic-Carbon
R6 = L-A, A-Aromatic-Carbon
R7 = L-A, A-Aromatic-Carbon
R8 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R9 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R10 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Reactants

Products