Index
Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Thiolate
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Azide
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Hydroxyl
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Carboxyl-H
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Thiolate
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Amino
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R4 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Carboxyl-H
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Azide
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Alkoxide
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Carboxyl-H
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Hydroxyl
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Alkoxide
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Azide
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Amino
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R4 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Thiolate
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Amino
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R4 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Hydroxyl
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products
Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Alkoxide
Condition to enforce:
R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon
Avoid formation of:
fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5
Reactants
Products