Index

Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Thiolate

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Azide

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Hydroxyl

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Carboxyl-H

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Thiolate

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Amino

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R4 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Carboxyl-H

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Azide

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Alkoxide

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Carboxyl-H

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Hydroxyl

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Alkoxide

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Azide

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Chlorine-and-Nu-Amino

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R4 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Thiolate

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Amino

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R4 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Iodine-and-Nu-Hydroxyl

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products

Imine-Nucleophilic-Substitution-Lg-Bromine-and-Nu-Alkoxide

References: 0,1

Condition to enforce:

R1 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon, Vinyl-Group, A-Alkoxide, Hydroxyl, A-Aliphatic-Nitrogen
R2 = H, A-Aliphatic-Carbon, A-Aromatic-Carbon
R3 = A-Aliphatic-Carbon, A-Aromatic-Carbon

Avoid formation of:

fragment = 3-membered-ring, 4-membered-ring, A-Cyclobutene, A-Cyclobutene-Aromatic, A-Cyclobutadiene, A-Cyclo-Double-Aromatic-pentene, A-Cyclopentene-Aromatic, bridged_meta_tether_2, A-Cyclo-Double-Aromatic-Pentene3, bridged_para_tether_2, bridged_para_tether_3, bridged_para_tether_4, bridged_para_tether_5, bridged_meta_tether_1, bridged_meta_tether_2, bridged_meta_tether_3, bridged_meta_tether_4, bridged_meta_tether_5

Reactants

Products